翻訳と辞書
Words near each other
・ Interlunar
・ Interleukin 23
・ Interleukin 23 subunit alpha
・ Interleukin 24
・ Interleukin 25
・ Interleukin 26
・ Interleukin 27
・ Interleukin 27 receptor, alpha subunit
・ Interleukin 28
・ Interleukin 28 receptor, alpha subunit
・ Interleukin 28B
・ Interleukin 29
・ Interleukin 3
・ Interleukin 30
・ Interleukin 31
Interleukin 32
・ Interleukin 33
・ Interleukin 34
・ Interleukin 35
・ Interleukin 36 receptor antagonist
・ Interleukin 37
・ Interleukin 4
・ Interleukin 5
・ Interleukin 5 receptor alpha subunit
・ Interleukin 6
・ Interleukin 7
・ Interleukin 8
・ Interleukin 8 receptor, alpha
・ Interleukin 8 receptor, beta
・ Interleukin 9


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Interleukin 32 : ウィキペディア英語版
Interleukin 32

Interleukin 32 is a protein that in humans is encoded by the IL32 gene.
==Function==

This gene encodes a member of the cytokine family. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNF-alpha from macrophage cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.〔

Interleukin 32 (IL-32) is a pro-inflammatory cytokine that can induce cells of the immune system (such as monocytes and macrophages) to secrete inflammatory cytokines, such as tumor necrosis factor-alpha (TNF-α) and IL-6. In addition, it can also induce the production of chemokines such as IL-8 and MIP-2 / CXCL2.
IL-32 can also support osteoclast differentiation but not osteoclast activation by regulating the MAPK/ERK pathway and the actin cytoskeleton.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Interleukin 32」の詳細全文を読む



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